Tablet Presentation

Each film coated tablet contains:
Oxcarbazepine IP 300 mg

Oxcarbazepine is an anti-epileptic drug. it is used to treat partial seizures.
It inhibits the abnormal electrical activity in the brain.
It blocks the nerve impulses that causes serious pain and seizures

Indications & Usage

In partial onset seizures

Mechanism of Action

It blocks the sodium channels. it prevents the opening and closing of nerve impulses and propagation of action potential in the neuron epilepsy is the condition where there is excessive firing of neurons.
It also inhibits the glutamatergic activity and enhances the overexcitation of neurons.
It also increases conductance of potassium and modulation of voltage gated calcium channels.

Pharmacokinetics

Absorption- It is absorbed orally
Protein Binding- It is mainly bound to albumin i.e. 40%
Metabolism- It undergoes glucuronidation
Excretion- It is excreted via urine

Side Effects

• Dizziness
• Drowsiness
• Vomiting
• Nausea
• Headache
• Constipation
• Difficulty in breathing

Contraindications

• Contraindicated in pregnancy
• Contraindicated in depression

Drug Interactions

• Melatonin
• Lamotrigine
• Ibuprofen
• Hydrocodone